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Follow these directions to put your DNA on display. You will not need phosphates at the end of the strands. The sugars (steel balls) attach directly to the magnetic rods on the stand. Make sure the polarity of the magnetic base-pairs (bp) are such that the strands make the strongest possible connection to the rods on the stand (see hint below). You may need to flip the end base-pair to optimize the magnetic connections to the top and bottom rods of the stand. Attach your DNA to the upper rods. While the ladder is hanging down, twist the left side of the ladder away from you, starting at the top base-pair (bp). Move down the bp ladder, slightly twisting the left side of each bp away from you until you have twisted the entire strand by almost a complete rotation (315°). DNA Display Hint: To make the most stable double helix, match up the polarities of the magnets as in the figure. If the stand magnet pole is N, then the two magnets from the base and phosphate should be connected at their S poles. The connections at both ends of the DNA are most critical, while the others are not as important. |